Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28 amino acid peptide renowned for its broad physiological roles such as vasodilation, anti-inflammatory activities, and the regulation of endocrine and exocrine systems. Produced in vital regions like the gastrointestinal tract and the central nervous system, VIP is essential for maintaining homeostasis. Its ability to modulate the immune system and reduce inflammation highlights its therapeutic potential in various medical conditions.
VIP nasal spray could be a helpful adjunct to GLP-1 receptor agonist therapy by enhancing insulin sensitivity and reducing inflammation, thereby potentially offering additional metabolic benefits for patients undergoing GLP-1 RA therapy.
Clinical Applications:
VIP nasal spray is strategically utilized to manage conditions such as CHRONIC INFLAMMATORY RESPONSE SYNDROME (CIRS), sarcoidosis, exposure to toxins, and other autoimmune and inflammatory diseases. The immunomodulatory effects of VIP significantly contribute to symptom relief and improved quality of life for patients. Additionally, VIP’s role in enhancing insulin sensitivity is invaluable for patients pursuing weight management, as it aids in improving glucose metabolism and reducing inflammatory responses to optimize metabolic health.